Physicians click their way to better prescriptions
(Springer) Is it time for all community-based doctors to turn to e-prescribing to cut down on the number of medication errors? According to Rainu Kaushal and colleagues from the Weill Cornell Medical College in New York, electronic prescriptions can dramatically reduce prescribing errors -- up to seven-fold. Their study of the benefits of e-prescribing in primary care practices appears online in the Journal of General Internal Medicine, published by Springer....
POSTED 03/10/2010 at 12:00 AM -- 
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Research findings expected to ease treatment of low neutrophil counts in cancer patients
(St. Jude Children's Research Hospital) New research led by St. Jude Children's Research Hospital investigators may change neutropenia treatment for all childhood cancer patients....
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Breast cancer drug fulvestrant appears more effective in the presence of CK8 and CK18
(Indiana University) Women's responsiveness to the second-line breast cancer drug fulvestrant may depend on whether the cancer cells are expressing two key proteins, Indiana University Bloomington scientists report in this month's Cancer Biology & Therapy....
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Genomatix gives a hand in the analysis of Wayne State's sequencing projects
(Genomatix Software GmbH) The C.S. Mott Center for Human Growth and Development at the Wayne State University School of Medicine installed a Genomatix Mining Station and a Genomatix Genome Analyzer last year at their labs in order to support the analysis of NextGen Sequencing data. Professor Stephen Krawetz , Director of Translational Reproductive Systems is utilizing the Genomatix systems to help analyze the cis and epigenetic elements that control many reproductive events, including cell-fate....
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LSUHSC researcher finds first inherited prostate cancer genetic mutation in African-American men
(Louisiana State University Health Sciences Center) Shahriar Koochekpour, M.D., Ph.D., assistant professor of microbiology and genetics at LSU Health Sciences Center New Orleans, led research that has discovered, for the first time, a genetic mutation in African-American men with a family history of prostate cancer who are at increased risk for the disease. Dr. Koochekpour identified an inheritable genetic defect in the receptor for the male hormone, androgen (testosterone), that may contribute to the development of prostate cancer and its progression....
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Risk for patients in the intensive care unit clearly reduced
(University Hospital Heidelberg) To get life-threatening diseases under control, patients in the intensive care unit usually are administered many medications at the same time. Even for experts, it is difficult to keep track of the variety of possible side effects and interactions. The team headed by Dr. Thilo Bertsche, director of the cooperation unit for clinical pharmacy at Heidelberg University Hospital, has now shown that physicians can reduce serious events resulting from drug interactions by about half with the help of the "AiDKlinik" drug information system....
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Patient and doctor expectations from joint replacement surgeries not always aligned
(Hospital for Special Surgery) While physicians strive to set realistic expectations for patients undergoing knee and hip joint replacements, a new study reported by Hospital for Special Surgery researchers reveals that doctor and patient expectations are sometimes not aligned....
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Research streamlines data processing to solve problems more efficiently
(North Carolina State University) Researchers at North Carolina State University have developed a new analytical method that opens the door to faster processing of large amounts of information, with applications in fields as diverse as the military, medical diagnostics and homeland security....
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BIDMC scientist Christopher Evans, Ph.D., honored by Orthopedic Research Society
(Beth Israel Deaconess Medical Center) Christopher Evans, Ph.D., director of the Center for Advanced Orthopedic Studies at Beth Israel Deaconess Medical Center and Maurice Edmond Mueller Professor of Orthopedic Surgery at Harvard Medical School, was presented with the 2010 Arthur Steindler Award at this week's annual meeting of the Orthopedic Research Society in New Orleans....
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Osteoporosis drug improves healing after rotator cuff surgery
(Hospital for Special Surgery) Tears in the shoulder's rotator cuff, a common sports injury, are painful and restricting. New research shows an approved therapy for osteoporosis, Forteo, may speed healing and improve patient outcomes, according to a preliminary study from Hospital for Special Surgery in New York....
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ATV and motocross sports -- high velocity toys merit caution
(American Academy of Orthopaedic Surgeons) Over the years, all terrain vehicles (ATVs) and motocross motorcycles have gained popularity and marketed as toys to consumers....
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Breakthroughs in treatment of spine and back conditions
(American Academy of Orthopaedic Surgeons) Approximately 21 million visits were made to physicians' offices due to back problems in 2006. While countless adults experience back pain and stiffness, many suffer from serious spine and back conditions -- including injury, herniated discs and the deterioration of the vertebrae. Three new studies presented at the 2010 Annual Meeting of the American Academy of Orthopaedic Surgeons detail advances in back care and treatment options for specific back and spine conditions....
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Youth baseball throwing arm injuries are rising dramatically
(American Academy of Orthopaedic Surgeons) Throwing arm injuries are on the rise in Little League and other youth baseball programs. After these injuries occur, many players are out for the season; others require surgery and must refrain from play for an even longer duration; still others sustain injuries so severe that they cause permanent damage and are unable to continue playing baseball....
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Quantity vs. quality: Long-term use of bone-building osteoporosis drugs
(American Academy of Orthopaedic Surgeons) Bisphosphonate treatments, proven to enhance bone density and reduce fracture incidence in post-menopausal women, may adversely affect bone quality and increase risk of atypical fractures of the femur when used for four or more years, according to preliminary research presented today at the 2010 Annual Meeting of the American Academy of Orthopaedic Surgeons....
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Pediatric sports injuries: the silent epidemic
(American Academy of Orthopaedic Surgeons) At today's 2010 Annual Meeting of the American Academy of Orthopaedic Surgeons, two separate studies focus on the dramatic rise of pediatric sports injuries in recent years....
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Way to go: MBL scientists identify driving forces in human cell division
(Marine Biological Laboratory) Using a novel imaging system for quantifying aspects of cell division in three dimensions, MBL scientists discover new interactions between sister kinetochores -- the protein bundles at the contact point between the two identical strands of a chromosome -- and the microtubule motors that help pull the strands apart....
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Papaya extract thwarts growth of cancer cells in lab tests
(University of Florida) Papaya extract seems to have a toxic effect on cancer cells in culture, suggesting a potential treatment. Scientists documented for the first time that papaya leaf extract boosts the production of key signaling molecules called Th1-type cytokines. This regulation of the immune system, in addition to papaya's direct anti-tumor effect on various cancers, suggests possible therapeutic strategies that use the immune system to fight cancers....
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Sonic hedgehog gene found in an unexpected place during limb development
(University of Florida) Sonic hedgehog is at work in mice limb buds in what is known as the ectoderm, the cell layer that gives rise to skin, researchers discovered. Finding Sonic hedgehog here is akin to discovering that yeast has crept from the batter to the frosting, where it has the surprising effect of limiting how much the cake rises. In this case, instead of causing appendages to grow in mice, Sonic hedgehog prevents digits from developing....
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New study questions benefits of elective removal of ovaries during hysterectomy
(Elsevier Health Sciences) Removal of the ovaries (bilateral oophorectomy) while performing a hysterectomy is common practice to prevent the subsequent development of ovarian cancer. This prophylactic procedure is performed in 55 percent of all US women having a hysterectomy, or approximately 300,000 times each year. An article in the March/April issue of the Journal of Minimally Invasive Gynecology suggests that this procedure may do more harm than good....
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2010 recipient of Minority Scholar Award will conduct clinical research on leukemia
(American Society of Hematology) Alison Walker, MD, has been selected to receive the ASH-AMFDP Award, and will begin her research in acute myeloid leukemia in July of this year....
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